Accession Number : ADA114613

Title :   Mammalian Toxicology Testing: Problem Definition Study. Part 1. Comparative Analysis Report.

Descriptive Note : Final rept. 15 Dec 80-5 Apr 81,

Corporate Author : LIFE SYSTEMS INC CLEVELAND OH

Personal Author(s) : Wynveen,R A ; Reuter,R H ; Davenport,R J

PDF Url : ADA114613

Report Date : Mar 1981

Pagination or Media Count : 133

Abstract : Global Army mammalian toxicology testing requirements were defined, and to some extent those that would be the responsibility of the U.S. Army Medical Research and Development Command (USAMRDC) were identified. Since no quantitative or qualitative description of the Army's toxicology capability exists, the unmet requirements could not be precisely defined. Approaches for meeting a portion of the USAMRDC's unmet requirements were compared and particular emphasis was placed on production testing for mammalian toxicology studies. The cost to fulfill unmet requirements will approach $30 million per year for the global Army, and if it is assumed that 30 to 60% of the requirements are the responsibility of the medical organizations, their annual budgets would need to be increased by $10 to $20 million. Funding should not be diverted from other MRDC priority programs. Additional capability and capacity for toxicology testing should be added only after balancing and specifying requirements, resolving responsibilities and obtaining budgetary commitments.

Descriptors :   *Toxicology, *Mammals, *Test methods, Army research, Medical research, Requirements, Costs, Chemicals, Budgets

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE