Accession Number : ADA115418

Title :   Topical Hazard Evaluation Program Procedural Guide.

Descriptive Note : Final rept. Oct 78-Sep 81,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Topper,Michael J ; Harvey,John G , Jr

PDF Url : ADA115418

Report Date : Jan 1982

Pagination or Media Count : 63

Abstract : Preliminary hazard evaluations of the above candidate insect repellant chemicals were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. Chemicals AI3-37565, 37567, 37569, 37570, 37571, 37572, 37574 and 38010 did not cause any skin irritation. Chemical AI3-37566 and 37578 caused mild primary skin irritation. Chemical AI3-37574 was noninjurious to the eyes of rabbits. Chemicals AI3-37565 and 37572 caused mild injury to the cornea and chemicals AI3-37566, 37567, 37569, 37570, 37571, 37578, and 38010 caused mild injury to the cornea and, in addition, some injury to the conjunctiva. (Author)

Descriptors :   *Toxicology, *Toxic hazards, *Insect repellents, Skin(Anatomy), Irritation, Eye, Rabbits, Cornea, Test and evaluation

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE