Accession Number : ADA115528

Title :   Investigations of Cross Immunity between Leishmania tropica (Jericho) and Leishmania braziliensis in Experimentally Infected Mystromys albacaudatus.

Descriptive Note : Annual rept. no. 1, Feb-Sep 79,

Corporate Author : VIRGINIA UNIV CHARLOTTESVILLE DEPT OF DERMATOLOGY

Personal Author(s) : Beacham,Bruce E

PDF Url : ADA115528

Report Date : Sep 1979

Pagination or Media Count : 18

Abstract : Methods have been outlined for storage and reconstitution of various leishmania strains to be used as a vaccine. Investigation of cross immunity between L. Tropica (Jericho) and L. braziliensis panamensis were made utilizing the African white tailed rat, mystromys albacaudatus, model. It was established that an ulcerogenic dose of L. tropica (Jericho) and L. braziliensis (panamensis) was 2 x 106 promastigotes. Preliminary results indicated that L. tropica (Jericho) infected M albacaudatus may develop immunity to infection with not only the homologus strain but also against L. braziliensis panamensis. (Author)

Descriptors :   *Immunity, *Leishmania, *Vaccines, Storage, Strains(Biology), Dosage, Immunization

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE