Accession Number : ADA116839

Title :   Hematologic Characterization of Naturally Occurring Malaria (Plasmodium inui) in the Cynomolgus Monkey (Macaca fascicularis).

Descriptive Note : Interim rept.,

Corporate Author : ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD

Personal Author(s) : Donovan,John C ; Stokes,William S ; Montrey,Richard D ; Rozmiarek,Harry

PDF Url : ADA116839

Report Date : 23 Apr 1982

Pagination or Media Count : 17

Abstract : Forty-three percent of 47 recently imported cynomolgus monkeys (Macaca fascicularis) were found to have malarial infections. The agent identified was Plasmodium inui. All infections were subclinical in nature. Parasitemias ranged from 10-900 parasites/cm mm of whole blood. Pre- and posttreatment hematologic values were evaluated following treatment with chloroquine. Treatment was effective in clearing parasitemias from 13 of 14 infected monkeys. Pretreatment values of hematocrit, hemoglobin and mean corpuscular volume were significantly different in infected animals compared to noninfected animals. (Author)

Descriptors :   *Malaria, *Plasmodium, *Chloroquine, Chemotherapy, Macaca fascicularis, Parasitemias, Hematology, Hemoglobin, Hematocrit, Level(Quantity), Physiological effects

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE