Accession Number : ADA118623

Title :   Studies on the Mechanism and Prevention of Decompression Sickness.

Descriptive Note : Final technical rept. 1 Jun 68-28 Feb 82,


Personal Author(s) : Chryssanthou,Chryssanthos

PDF Url : ADA118623

Report Date : 12 Jul 1982

Pagination or Media Count : 155

Abstract : The studies focused on three main areas: Decompression Sickness, Dysbaric Osteonecrosis and Dysbaric Alteration of the Blood-Brain Barrier. On decompression sickness, attempts were made to elucidate pathogenetic mechanisms. Several hypotheses were advanced and novel pathogenetic concepts were proposed. On the basis of new theoretical considerations we were able to develop means for the prevention or amelioration of the disease. Regarding dysbaric osteonecrosis, we developed an animal model which permitted studies on the etiology predisposition and pathogenesis of the disorder. The most recrnt investigations covered by this report involve dysbaric modification of blood-tissue barriers, an observation which was made in our Laboratories few years ago. The report includes an overview (summary) of the investigations conducted in these areas with references to pertinent publications. In lieu of detailed description of the work done, reprints to pertinent publications. In lieu of detailed description of the work done, reprints of representative articles have been attached. We hope that this material might be of help to those interested in the fields of dysbaric disroders.

Descriptors :   *Decompression sickness, Prevention, Blood, Brain, Lung, Barriers, Pathogenesis, Reports, Mice, Therapy, Reprints

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE