Accession Number : ADA119731

Title :   Laser Irradiation of SV40 DNA.

Descriptive Note : Technical rept.,

Corporate Author : HOWARD UNIV WASHINGTON DC DEPT OF CHEMISTRY

Personal Author(s) : Johnson-Thompson,Marian ; Halpern,Joshua B ; Jackson,William M ; George,Jay

PDF Url : ADA119731

Report Date : 17 Sep 1982

Pagination or Media Count : 18

Abstract : Simian virus 40 DNA was irradiated by a high intensity ArF excimer laser. Analysis by gel electrophoresis, neutral sucrose gradient analysis, and alkaline sucrose gradient analysis showed that the laser irradiation leads to breaking of the sugar phosphate backbone in a sequential manner at random sites. The causitive process is either attack by laser generated free radicals or two photon direct scission. (Author)

Descriptors :   *Deoxyribonucleic acids, *Photons, *Ultraviolet lasers, *Radiation effects, *Photochemical reactions, Fluorides, Viruses

Subject Categories : Biochemistry
      Radiation and Nuclear Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE