Accession Number : ADA130159

Title :   Mutagenic Potential of the Holston Compounds: Virgin DMSO, DMSO Recycle Solvent and DMSO Evaporator Sludge.

Descriptive Note : Final rept. 3 Jan-20 Mar 83,

Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s) : Sauers,Leonard J ; Kellner,Thomas P ; Fruin,John T

PDF Url : ADA130159

Report Date : Jun 1983

Pagination or Media Count : 44

Abstract : The mutagenic potential of the Holston Compounds (Virgin DMSO DMSO Recycle Solvent, and DMSO Evaporator Sludge) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537, and TA 1538 were exposed to doses ranging from 0.1 ml of a 100% to ml of a 0.032% solution. Negative mutagenic responses were observed for the Virgin DMSO and DMSO Recycle Solvent. Mutgenic potential was observed for the DMSO Evaporator Sludge. (Author)

Descriptors :   *Sulfoxides, *Toxicology, *Methyl sulfoxide, Mutagens, Bioassay, Microsomes

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE