Accession Number : ADA132618

Title :   Heat Exchange Following Atropine Injection Before and AFter Heat Acclimation,

Corporate Author : ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA

Personal Author(s) : Kolka,Margaret A ; Holden,William L ; Gonzalez,Richard R

PDF Url : ADA132618

Report Date : Aug 1983

Pagination or Media Count : 16

Abstract : The effect of saline and atropine injection (2 mg, im) on eight healthy, male subjects before and after heat acclimation was studied while each subject did treadmill walking in a hot-dry environment. Partitional calorimetric analysis was done for the periods in which maximum sweat inhibition occurred (30 min). Mean skin temperature (T sk), rectal temperature and heart rate was continuously observed. Evaporative loss from the skin was calculated by changes in body weight (Sauter balance); heat transfer coefficients were defined by Nishi equations. A prediction of sweat inhibition based on an analysis of heat storage and its effect on a theoretical temperature which can be graphed on a psychrometric chart, was developed. A rational effective temperature (ET*) defined as the T sub 0 at the intersection of the 50% rh which emcompasses total heat exchange was used to compare the effects of atropine before and after heat acclimation. The results show that heat acclimation reduced ET* by some 2.5 C when compared to the unacclimated state after atropine injection. Thus, heat acclimation reduces the hazards of heat stroke caused by exercise in the heat with atropine injection.

Descriptors :   *Atropine, *Exercise(Physiology), Heat, Acclimatization, Body temperature, Perspiration, Rates, Heat transfer, Coefficients

Subject Categories : Stress Physiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE