Accession Number : ADA133084

Title :   Primary Dermal Irritation Potential of the Holston Compounds. Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge.

Descriptive Note : Final rept. 3 Feb-10 Mar 83,

Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s) : Lewis,Carolyn M ; Kellner,Thomas P

PDF Url : ADA133084

Report Date : Aug 1983

Pagination or Media Count : 31

Abstract : The Holston Compounds designated DMSO Recycle Solvent (TP013), Virgin DMSO (TP014), and DMSO Evaporator Sludge (TP015) were tested for primary dermal irritation potential on rabbits. The study was conducted in compliance with the Good Laboratory Practice Regulations. While all three compounds caused slight erythema on a few animals, the average scores were low enough for all three compounds to be classified as non-irritating after one application. (Author)

Descriptors :   *Methyl sulfoxide, Skin(Anatomy), Irritation, Rabbits, Indexes(Ratios), Physiological effects

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE