Accession Number : ADA133740

Title :   Interaction of Anti-G Measures and Chest Wall Mechanics in Determining Gas Exchange.

Descriptive Note : Annual progress rept. 1 Apr 82-31 Mar 83,

Corporate Author : VIRGINIA MASON RESEARCH CENTER SEATTLE WA

Personal Author(s) : Modell,Harold I

PDF Url : ADA133740

Report Date : May 1983

Pagination or Media Count : 40

Abstract : Efforts during this reporting period have been directed in three areas: (1) Examination of regional intrapleural pressure changes during +Gz stress in the pig; (2) Development of an inexpensive assist/control, volume limited animal ventilator; and (3) Determining the influence of chest wall motion on gas exchange during mechanical ventilation in dogs. Studies assessing regional intrapleural pressure changes during +Gz stress in the dog were repeated in similar sized pigs to determine the role of chest wall mechanics in determining these changes. When the G-suit abdominal bladder was used, increases in regional intrapleural pressure greater than those seen in analogous dog experiments were observed. These results imply that, as the chest wall becomes less compliant, the degree of lung compression attributable to +Gz stress without G-suit application should deminish. In another series of experiments, gas exchange during assisted and controlled ventilation were compared in an attempt to ascertain whether an active effort by chest wall muscles coordinated with inspiration can influence gas exchange. The data obtained indicate that an inspiratory muscular effort enhances gas exchange. Measured gas exchange parameters suggest that this enhancement is the result of a redistribution of perfusion rather than a redistribution of ventilation.

Descriptors :   *Stress(Physiology), *Gas exchange(Biology), Lung, Swine, Dogs, Thorax, Motion, Pressure, G suits, Parameters, Muscles, Control, Volume

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE