Accession Number : ADA134545

Title :   Toxicological Assessment of ABATE (Tradename) (0,0,0',0'-Tetramethyl-0,0'-Thio-Di-P-Phenylene Phosphorothioate) Administered Orally and Dermally to Mated and Nonmated Female Rabbits, April 1983.

Descriptive Note : Final rept. Sep 79-Aug 83 on Phase 4,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Angerhofer,Richard A ; Weeks,Maurice H

PDF Url : ADA134545

Report Date : 02 Nov 1983

Pagination or Media Count : 50

Abstract : This study was designed to assess the teratologic potential of ABATE following repeated oral or dermal administration of the compound to pregnant rabbits during the major period of organogenesis. There were no teratologic effects in New Zealand White rabbits associated with repeated oral or dermal administration of ABATE at levels which produced a toxic effect. Although these studies have shown that ABATE should not cause teratogenic effects in its intended use, chronic studies should be performed to further define any potential long term toxicity.

Descriptors :   *Toxicology, *Insecticides, *Lice, Oral dosage, Physiological effects, Skin(Anatomy), Test and evaluation, Rabbits, Pregnancy, Toxic hazards

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE