Accession Number : ADA138922

Title :   The Manufacture and Study of Hemoglobin-Saline Solution.

Descriptive Note : Final rept.,

Corporate Author : MICHAEL REESE HOSPITAL AND MEDICAL CENTER CHICAGO ILL

Personal Author(s) : Moss,G S

PDF Url : ADA138922

Report Date : 25 Feb 1981

Pagination or Media Count : 15

Abstract : Studies completed during the term of this contract include: Sensitivity of the IL 282 Co-oximeter to low hemoglobin concentration and high proportions of methemoglobin; Performance of the oxygen-hemoglobin dissociation analyzer 'Hem-O-Scan', compared with the IL 282 Co-oximeter; Determination of serum Creatinine in the presence of high concentrations of free hemoglobin; Large vollume preparation of pyridoxalated stroma-free hemoglobin with high in vivo P sub 50; Oxygen transport by pyridoxalated stroma-free hemoglobin; Cardiac response during hemodilution with stroma-free hemoglobin solutions having different oxygen affinities; Hemodynamic response in the baboon Extreme Hemodilution using stroma-free hemoglobin; A quantitative analysis of alterations in PvO2; and The contribution of hemoglobin concentration and P sub 50 to oxygen transport during exchange transfusion with hemoglobin solutions.

Descriptors :   *Hemoglobin, Blood transfusion, Erythrocytes, Saline solution, Blood analysis, Test methods, Oxygen, Dissociation, Creatinine, Preparation, Transport properties, Heart rate, Dilution, Baboons

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE