Accession Number : ADA139966

Title :   Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-38274, AI3-38276, and AI3-38279, US Department of Agriculture Proprietary Chemicals, February - November 1983.

Descriptive Note : Final rept.,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Wade,J V

PDF Url : ADA139966

Report Date : 03 Apr 1984

Pagination or Media Count : 10

Abstract : The technical grade chemicals produced no greater than mild primary irritation of the intact skin and of the skin surrounding an abrasion. The 24 percent (w/v) solutions of these chemicals in 95 percent ethanol which were applied during photoirritation studies produced mild to moderate primary irritation of the intact skin, without ultraviolet (UV) irradiation. Chemical AI3-38276 produced a photochemical irritant reaction upon irradiation with UV light which was significantly more severe than the primary irritation previously noted. Additionally, although these ethanol solutions were colorless, they produced a marked yellow discoloration of the skin upon application. All three chemicals produced moderate injury to the cornea and, in addition, produced some injury to the conjunctiva.

Descriptors :   *Insect repellents, *Toxicity, Toxic hazards, Test and evaluation, Eye, Irritation, Skin(Anatomy), Rabbits

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE