Accession Number : ADA140159

Title :   Blood Preservation Study.

Descriptive Note : Annual progress rept.,

Corporate Author : CITY OF HOPE NATIONAL MEDICAL CENTER DUARTE CA

Personal Author(s) : Beutler,E

PDF Url : ADA140159

Report Date : 30 Apr 1979

Pagination or Media Count : 28

Abstract : Although the 21 day shelf life of red cells stored in acid-citrate-dextrose or citrate-phosphate-dextrose solution represents a workable system for blood storage, it is unsatisfactory in three major respects: (1) A shelf life of only 21 days makes the stockpiling of blood impossible. (2) While blood is considered to be usable until the 21st day of storage, only about 70% of the red cells in 21 day-old units are useful to the patient. (3) The 2,3-diphosphoglycerate (2,3-DPG) content of blood stored in ACD declines rapidly after one or two days of storage, while in CPD the decline of 2,3-DPG levels is delayed for only one week. Work has been directed toward resolution of the three problems associated with liquid blood storage.

Descriptors :   *Blood preservation, Blood storage, Shelf life, Erythrocytes, Stockpiles, Adenine, Hematocrit, Blood platelets

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE