Accession Number : ADA140187

Title :   Development of Biodegradable Implants for Use in Maxillofacial Surgery.

Descriptive Note : Annual rept. Oct 81-Jun 82,


Personal Author(s) : Lewis,D H ; Dunn,R L ; Casper,R A

PDF Url : ADA140187

Report Date : Jun 1982

Pagination or Media Count : 18

Abstract : The objective of the project is to develop high-strength, bioabsorbable materials useful in the treatment and management of maxillofacial injuries. The specific goal for the current contract year has been the attainment of high-strength, high-modulus, biodegradable ceramic fibers for use in the reinforcement of biodegradable polymeric fracture-fixation plates. To meet this goal, we have examined the spinnability and processibility of beta-tricalcium phosphate (whitlockite) and phosphate-free calcium aluminate. In studies conducted during the previous 2 years, composites fabricated from poly(DL-lactide)(DL-PLA) and commercially available, nonbiodegradable ceramic fibers were shown to provide sufficient strength and rigidity for use in the repair of mandibular fractures in dogs. Our work during the current renewal period was therefore been directed toward obtaining biodegradable ceramic fibers with mechanical properties sufficient for the fabrication of a totally biodegradable fracture-fixation appliance.

Descriptors :   *Ceramic fibers, *Surgical implantation, *Mandible, *Bone fractures, Reinforcing materials, Polymers, Plates, Spinning(Industrial processes), Processing, Calcium compounds, Phosphates, Aluminates, Mechanical properties, Fabrication, Heat treatment, Sintering, Encapsulation, Biodeterioration, Dogs

Subject Categories : Medical Facilities, Equipment and Supplies
      Refractory Fibers

Distribution Statement : APPROVED FOR PUBLIC RELEASE