Accession Number : ADA140201

Title :   Development of Biodegradable Implants for Use in Maxillofacial Surgery.

Descriptive Note : Annual technical rept. Aug 79-Sep 81,

Corporate Author : SOUTHERN RESEARCH INST BIRMINGHAM AL

Personal Author(s) : Lewis,D H ; Dunn,R L ; Casper,R A

PDF Url : ADA140201

Report Date : 28 Oct 1981

Pagination or Media Count : 67

Abstract : Biodegradable polymers were synthesized and fabricated into fracture-fixation plates for use in the management of maxillofacial injuries. The plates, however, did not possess sufficient strength and ridigity for properly immobilizing the healing bone. The biodegradable resins were subsequently reinforced with both ceramic and carbon fibers by a lamination process. The resulting appliances were not totally biodegradable, but served as a model study for methods to obtain the desired composite material properties. In vitro experiments with these materials showed that the composites were capable of retaining sufficient strength and integrity, in a pseudo-physiological environment, throughout the period normally required for formation of primary ossious union and subsequent healing. Implantation in dogs, conducted by the U. S. Army Institute of Dental Research, demonstrated the suitability of the fiber-reinforced resin systems for use in the promotion of healing in mandibular defects. Both biodegradable fibers and crosslinkable biodegradable resins were examined as methods for obtaining a totally biodegradable fixation system.

Descriptors :   *Ceramic fibers, *Surgical implantation, *Mandible, *Bone fractures, Polymers, Biodeterioration, Synthesis, Fabrication, Plates, Strength(Mechanics), Rigidity, Healing, Bones, Carbon fibers, Reinforcing materials, Reinforced plastics, Composite materials, Dogs

Subject Categories : Medical Facilities, Equipment and Supplies
      Refractory Fibers
      Laminates and Composite Materials
      Plastics

Distribution Statement : APPROVED FOR PUBLIC RELEASE