Accession Number : ADA140419

Title :   Therapeutic Effectiveness of Cryopreserved Autologous Platelets in the Treatment of Thrombocytopenic Dogs.

Descriptive Note : Technical rept.,

Corporate Author : BOSTON UNIV MA SCHOOL OF MEDICINE

Personal Author(s) : Melaragno,A J ; Doty,A J ; Dittmer,J ; Vecchione,J J ; Valeri,C R

PDF Url : ADA140419

Report Date : 08 Apr 1982

Pagination or Media Count : 25

Abstract : Canine platelets were preserved in the frozen state with 6% DMSO in a -80 C mechanical freezer. The recovery of platelets after the freeze-thaw-wash procedure was about 70%, and posttransfusion recovery values were about 40% those of fresh platelets. The washed previously frozen platelets were hemostatically effective in supporting lethally irradiated dogs through prolonged periods of thrombocytopenia.

Descriptors :   *Blood platelets, *Therapy, *Thrombocytopenia, Blood preservation, Cryogenics, Freezing, Survival(General), Recovery, Methyl sulfoxide, Irradiation, Dogs, Blood transfusion

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE