Accession Number : ADA140720

Title :   Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Descriptive Note : Annual rept. 1 Sep 78-31 Aug 79,


Personal Author(s) : Bishop,D H L

PDF Url : ADA140720

Report Date : Aug 1979

Pagination or Media Count : 26

Abstract : We have (1) characterized several of the major structural components of the Phlebotomus fever group viruses (Robeson, et al, 1979), and (2) isolated and begun to characterize several temperature sensitive (ts), conditional lethal, mutants of Punta Toro (PT) virus. In addition at the request of WRAIR, we have (3) demonstrated the feasibility of using oligonucleotide fingerprinting to distinguish Dengue (DEN) virus serotypes using cloned Aedes albopictus cells to produce labeled virus. These procedures have now been adopted by WRAIR personnel for their Dengue virus studies.

Descriptors :   *Sandfly fever virus infection, *Dengue, Genetics, Molecules, Mutations, Isolation, Identification, Nucleotides, Serology

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE