Accession Number : ADA140721

Title :   Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Descriptive Note : Annual rept. 1 Sep-31 Aug 82,


Personal Author(s) : Bishop,D H L

PDF Url : ADA140721

Report Date : 28 Aug 1982

Pagination or Media Count : 32

Abstract : We have: (1) undertaken heterologous recombination analyses involving dualinfections with wild-type PT and SFS viruses, PT and CHG viruses, PT and ICO viruses, or PT and KAR viruses; (2) performed analyses of the homologous and heterorlogous virus interference capabilities of PT (or ICO) virus preparations that contain DI particles; (3) indicated that at the structural level the tick-borne uukuviruses (Uukuvirus genus, Bunyaviridae family) closely resemble phleboviruses; characterized the unassigned tick-borne Dhori (DHO) virus, a virus that heretofore has been considered as a possible member of the family, has been undertaken in order to determine if this virus has the structural attributes of phleboviruses (or members of other defined genera of the family); and (5) cloned and sequenced complete copies of influenza A/RR/8/34 RNA segments 2 and 3, as well as bunyavirus SSH S RNA species.

Descriptors :   *Sandfly fever virus infection, *Viruses, Genetics, Molecules, Identification, Isolation

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE