Accession Number : ADA140792

Title :   A Six-Month Clinical Evaluation of Decalcified Freeze-Dried Bone Allografts in Periodontal Osseous Defects.

Descriptive Note : Final rept.,


Personal Author(s) : Quintero,G ; Mellonig,J T ; Gambill,V M ; Pelleu,G B , Jr

PDF Url : ADA140792

Report Date : 15 Dec 1983

Pagination or Media Count : 9

Abstract : The OSTEOGENIC POTENTIAL of decalcified freeze-dried bone allografts in the treatment of human periodontal osseous defects was evaluated over a 6 month period. Cortical bone, obtained under sterile conditions from a human donor within 24 hours after death, was decalcified, freeze-dried and ground to a particle size of 250 to 500 micrometers. Twenty-seven osseous defects with one-, two- and wide three-wall morphology were treated. Clinical measurements were made with a stent and a calibrated periodontal probe before surgery, at the time of surgery, and at re-entry. The combined mean osseous regeneration for all defects was 2.4 mm. This represented a 65% mean bone-fill of the original defect. The findings demonstrate that decalcified freeze-dried bone allograft has potential as an osseous grafting material in periodontal therapy.

Descriptors :   *Bones, Freeze drying, Surgical transplantation, Teeth, Dentistry, Osteogenesis

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE