Accession Number : ADA141025

Title :   Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-38862a, AI3-38863a, AI3-39048a, AI3-39049a, AI3-39050a, and AI3-39051a.

Descriptive Note : Final rept. May 83-Mar 84,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Wade,J V

PDF Url : ADA141025

Report Date : 10 May 1984

Pagination or Media Count : 9

Abstract : Chemicals AI3-38862a, AI3-39048a, AI3-39049a, AI3-39050a, and AI3-39051a produced moderate to severe primary irritation of the intact skin and of the skin surrounding an abrasion and, in addition, produced necrosis and/or eschars. Chemical AI3-38863a produced mild primary irritation of the intact skin and of the skin surrounding an abrasion. The 25% (w/v) solution of chemical AI3-38863a applied during photoirritation testing produced moderate primary irritation of the intact skin, without ultraviolet irradiation. Chemical AI3-38863a produced moderate injury to the cornea and, in addition, some injury to the conjunctiva. All chemicals demonstrated low to slight toxicity upon ingestion.

Descriptors :   *Insect repellents, *Toxicity, Irritation, Skin(Anatomy), Eschar, Cornea, Test and evaluation, Rabbits, Rats

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE