Accession Number : ADA141209

Title :   Motor Performance in Irradiated Rats as a Function of Radiation Source, Dose, and Time Since Exposure.

Descriptive Note : Final rept. Jan 83-Jan 84,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX

Personal Author(s) : Wheeler,T G ; Hardy,K A ; Anderson,L B ; Richards,S

PDF Url : ADA141209

Report Date : Mar 1984

Pagination or Media Count : 16

Abstract : The study reported here has employed a single species (rats) and a single motor task (rotarod), and has evaluated performance as a function of time after irradiation exposure across a fixed dose range (0-1200 rads) using four radiation sources (electrons, neutrons, protons, and X-rays). Only minor differences in performance were noted as a function of radiation source, with neutrons producing the largest deficits. All sources produced a clear dose-response curve for each of the four times (1, 8, 15, and 22 days after irraditaion). The LD50/15 for the various exposures were found to be: X-rays, 1125 rads; electrons, 810 rads; protons, 675 rads; and neutrons, 265 rads.

Descriptors :   *Radiation effects, *Ionizing radiation, *Motor reactions, Behavior, Rats, Irradiation, Radiation dosage, Exposure(Physiology), X rays, Electrons, Protons, Neutrons

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE