Accession Number : ADA180408

Title :   Neurochemical Dissociation of Memory Systems.

Descriptive Note : Technical rept.,

Corporate Author : MINNESOTA UNIV MINNEAPOLIS DEPT OF PSYCHOLOGY

Personal Author(s) : Nissen,Mary J. ; Knopman,David S. ; Schacter,Daniel L.

Report Date : DEC 1986

Pagination or Media Count : 40

Abstract : The administration of scopolamine, an anticholinergic drug, reduced the ability to recall and recognize stimuli presented previously -- an ability thought to require declarative memory. In contrast, measures of procedural memory were unaffected by scopolamine: Performance on a serial reaction time task incorporating a repeating stimulus and response sequence showed no difference in acquisition and retention of the sequence after scopolamine or saline. These results suggest that the cholinergic system is required for declarative but not procedural memory. Keywords: Neurochemistry.

Descriptors :   *SCOPOLAMINE, *CHOLINESTERASE INHIBITORS, *MEMORY(PSYCHOLOGY), RECALL, CHOLINERGIC NERVES, DISSOCIATION, NEUROCHEMISTRY, SEQUENCES, STIMULI, ACQUISITION, DRUGS, MEMORY DEVICES, RESPONSE

Subject Categories : Biochemistry
      Psychology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE