Accession Number : ADA181983

Title :   Increases in Aldosterone Precede Those of Cortisol During Graded Exercise.

Descriptive Note : Interim rept.,

Corporate Author : NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA

Personal Author(s) : Buono,Michael J ; Yeager,John E

PDF Url : ADA181983

Report Date : 06 Jan 1987

Pagination or Media Count : 12

Abstract : Aldosterone and cortisol are the two major hormones secreted by the human adrenal cortex. Exercise is one of the stresses known to increase the levels of both of these hormones, although the intensity of exercise needed to elicit secretion is different for the two. The purpose of this study was to determine the intensity threshold needed to elicit increases in plasma levels of aldosterone and cortisol during graded exercise in humans. Both potassium and angiotensin II were significantly correlated with aldosterone during exercise, which suggests that both are important stimuli for aldosterone secretion during graded exercise. Aldosterone and cortisol were both increased by graded exercise to exhaustion. Aldosterone was increased at exercise intensities greater than 60% VO2 max. The increase in aldosterone preceded cortisol increase, a finding which is consistent with other studies of stimulus-secretion coupling in the adrenal cortex.

Descriptors :   *CORTISOL, *ALDOSTERONE, *SECRETION, *EXERCISE(PHYSIOLOGY), ADRENAL CORTEX, INTENSITY, FATIGUE(PHYSIOLOGY), HUMANS, STRESSES, HORMONES, THRESHOLD EFFECTS, BLOOD PLASMA, LEVEL(QUANTITY), ADRENAL CORTEX HORMONES, POTASSIUM, STIMULI

Subject Categories : Stress Physiology
      Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE