Accession Number : ADA182184

Title :   The Physiological Basis of a Theory for Synapse Modification.

Descriptive Note : Technical rept.,

Corporate Author : BROWN UNIV PROVIDENCE RI CENTER FOR NEURAL SCIENCE

Personal Author(s) : Bear,Mark F ; Cooper,Leon N ; Ebner,Ford F

PDF Url : ADA182184

Report Date : 29 Jun 1987

Pagination or Media Count : 36

Abstract : The functional organization of the cerebral cortex is modified dramatically by sensory experience during early postnatal life. The basis of these modifications is a type of synaptic plasticity that may also contribute to some forms of adult learning. The question of how synapses modify according to experience has been approached by determining theoretically what is required of a modification mechanize to account for the available experimental data in the developing visual cortex. The resulting theory states precisely how certain variables might influence synaptic modifications. this insight has led to the development of a biologically plausible molecular model for synapse modification in the cerebral cortex.

Descriptors :   *LEARNING, *CEREBRAL CORTEX, *SYNAPSE, ORGANIZATIONS, MODIFICATION, VISUAL CORTEX, MODELS, MOLECULAR STRUCTURE, NEUROCHEMISTRY, NEUROCHEMICAL CODING

Subject Categories : Anatomy and Physiology
      Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE