Accession Number : ADA184235

Title :   Mainframe Computer Programs for Rapid Analysis of Hybridoma Screening Data.

Descriptive Note : Summary rept. 1 Oct 84-30 Sep 85,

Corporate Author : CALIFORNIA UNIV OAKLAND NAVAL BIOSCIENCES LAB

Personal Author(s) : Neuschatz,Andrew M ; Miller,Paul L ; Karu,Alexander E

PDF Url : ADA184235

Report Date : Jan 1985

Pagination or Media Count : 2

Abstract : Most laboratories that currently produce large numbers of hybridomas grow them and screen their media by immunoassay in 96-well plates. Robotic systems are commercially available for sterile sampling, feeding and expansion of hybridomas. We have written a program package in microsoft Pascal that converts the records for a Dynatech Autoprep automated hybridoma sampler and a Flow, Multiskan enzyme immunoassay reader to an ASCII database format, merges them, and creates tables which can be sorted by any parameter (eg. source plate/well, target plate/well, or assay result) and a histogram from which the best responding hybridomas can be selected.

Descriptors :   *ROBOTICS, *IMMUNOASSAY, ASSAYING, DATA BASES, FORMATS, COMPUTER PROGRAMS, SAMPLING, MEDICAL COMPUTER APPLICATIONS, CULTURES(BIOLOGY), SELECTION, ENZYMES

Subject Categories : Computer Programming and Software
      Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE