Accession Number : ADA184308

Title :   Use of DNA Probes for Diagnosis of Infectious Diseases.

Descriptive Note : Summary rept. 1 Oct 86-30 Sep 87,

Corporate Author : CALIFORNIA UNIV OAKLAND NAVAL BIOSCIENCES LAB

Personal Author(s) : Kingsbury,David T

PDF Url : ADA184308

Report Date : Jan 1987

Pagination or Media Count : 6

Abstract : DNA hybridization is well established as an essential tool in modern molecular biology. In the past few years an increasing number of investigators have applied this technique to the detection and identification of a variety of infectious agents. A review of the scientific literature suggests that at the present time there are more than 20 DNA probes suitable for diagnostic purposes. The limiting factor in their full implimentation as a diagnostic test is the development of a supporting 'system', including suitable procedures for sample preparation and a high specific activity, non-radioactive DNA tagging procedure.

Descriptors :   *DIAGNOSIS(MEDICINE), *INFECTIOUS DISEASES, *DEOXYRIBONUCLEIC ACIDS, PATHOGENIC MICROORGANISMS, PROBES, HYBRIDIZATION, MOLECULAR BIOLOGY

Subject Categories : Medicine and Medical Research
      Genetic Engineering and Molecular Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE