Accession Number : ADA184838

Title :   Studies on Syntheses of Amine-Carboxyboranes (Boron Analogues of Amino Acids) and Derivatives.

Descriptive Note : Final rept. 1 Sep 83-31 May 87,

Corporate Author : DUKE UNIV DURHAM NC

Personal Author(s) : Spielvogel, Bernard F ; McPhail, Andrew T

PDF Url : ADA184838

Report Date : 17 Aug 1987

Pagination or Media Count : 5

Abstract : The principal goal of this research has been the synthesis and characterization of boron analogues of important biologically active molecules such as the amino acids. During this period of research synthesis were developed for esters and amides of a variety of simple boron analogues of amino acids. Also, routes to boron analogues of choline, acetylcholine and substituted acetylcholines were developed. Collaborative studies on the biological activity of many of these compounds were carried out by processor Iris H. Hall at University of North Carolina.

Descriptors :   *ORGANOBORANES, CARBOXYL GROUPS, AMINES, AMINO ACIDS, SYNTHESIS(CHEMISTRY)

Subject Categories : Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE