Accession Number : ADA185271

Title :   Radiofrequency Radiation and Cellular Secretory Processes.

Descriptive Note : Final rept. Feb 83-Dec 85,

Corporate Author : GEORGE WASHINGTON UNIV MEDICAL CENTER WASHINGTON DC DEPT OF ANATOMY

Personal Author(s) : Albert, Ernest N ; Slaby, Frank

PDF Url : ADA185271

Report Date : Aug 1987

Pagination or Media Count : 35

Abstract : The purpose of this study was to investigate the effect of unmodulated 915-MHz radiation on the secretory processes of exocrine and endocrine cells under in vitro conditions. Pancreatic tissue slices were exposed to 915-MHz radiation in a Crawford cell exposure system. Sham-exposed slices were either incubated at 37 C or 40 C. These slices were pulse-labeled with tritiated L-leucine and the labeled secretory proteins were determined by autoradiography and counting of silver grains. In another experiment, amylase secretion from exposed and sham-exposed pancreatic slices was determined. The results suggest that radiation exposure can alter exocrine and endocrine secretions under conditions where the microwave energy produced hyperthermia in localized areas.

Descriptors :   *RADIATION EFFECTS, *MICROWAVES, *SECRETION, *PANCREAS, PROTEINS, GLYCOSIDE HYDROLASES, HYPERTHERMIA, TRANSPORT PROPERTIES, PITUITARY HORMONES, PEPTIDES, KINETICS, INCUBATION, RATS

Subject Categories : Radiobiology
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE