Accession Number : ADA185680

Title :   Studies of Infection and Dissemination of Rift Valley Fever Virus in Mosquitoes.

Descriptive Note : Annual rept. 15 May 86-14 May 87,

Corporate Author : OHIO UNIV ATHENS

Personal Author(s) : Romoser, William S

PDF Url : ADA185680

Report Date : 02 Jul 1987

Pagination or Media Count : 35

Abstract : WE ARE ENGAGED IN A MULTIMETHOD STUDY OF Rift Valley fever virus in vector and hypothetical vector mosquitoes. We have found that (1) early dissemination and possible early or rapid transmission can occur in Culex pipiens; (2) evidence from several standpoints supports the idea of virus escape from the gut lumen in the region of the foregut-midgut junction; (3) the basal lamina may act as a midget barrier of at least retard viral passage; (4) RVF virus is capable of infecting most tissues in the mosquito hemocoel and may exert its pathological effects both by general depletion of energy stores and by interfaces with regulatory proceses; (5) the fat body may be an important amplifying tissue; (6) in Aedes mcintoshi, a species strongly suspected of transovarially maintaining RFV in Kenya, the follicular epithelia and eggs are, at least in some cases, susceptible to infection. Keywords: Disease vectors.

Descriptors :   *CULICIDAE, *DISEASE VECTORS, *RIFT VALLEY FEVER VIRUS, AEDES, CULEX, DISTRIBUTION, EGGS, FATS, INFECTIOUS DISEASES, KENYA, PATHOLOGY, VIRUSES, CELLS(BIOLOGY)

Subject Categories : Microbiology
      Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE