Accession Number : ADA185787

Title :   Phosphoproteins in Neuronal Function. Proceedings of the International Workshop (2nd) Held in Utrecht, Netherlands on 2-5 September 1985.

Descriptive Note : Final technical rept. 1 Jul-31 Dec 86,

Corporate Author : NORTHWESTERN UNIV EVANSTON IL COLL OF ARTS AND SCIENCES

Personal Author(s) : Routtenberg, Aryeh ; Gispen, W. H.

Report Date : 1986

Pagination or Media Count : 408

Abstract : This is the book of papers from the Second International Workshop on Brain Phosphoprotein function held in Utrecht. Partial Contents: Protein Phosphorylation and Polyphosphoinositide Metabolism; Ligand-stimulated turnover of inositol lipids in the nervous system; The role of inositol phosphates in intracellular calcium mobilization; Possible roles of protein kinase C in signal transduction in nervous tissues; Polyphosphoinositides, phosphoproteins and receptor function in rabbit iris smooth muscles; Pharmacological aspects of the inositide response in the central nervous system: the muscarinic acetylcholine receptor; Ion Channels: Modulation of ion channels by Calcium activated protein phosphorylation: a biochemical mechanism for associative learning; Cyclic nucleotides as modulators and activators of ionic channels in the nerve cell membrane; Receptors: Phosphorylation of the nicotinic acetylcholine receptor; Molecular mechanisms involved in the desensitization of dopamine receptors in slices of corpus striatum; Growth factor activation of protein kinase C-dependent and -independent pathways of protein phosphorylation in fibroblasts; relevance to activation of protein kinase C in neuronal tissues; Plasticity: Synaptic plasticity and protein kinase C; Protein phosphorylation in the nerve growth cone; Long-term potentiation and 4-aminopyridine-induced changes in protein and lipid phosphorylation in the hippocampal slice; Phosphorylation/dephosphorylation mechanisms in coated vesicles; Cyclic nucleotide- and calcium-dependent protein phosphorylation in rat pineal gland: physiological and pharmacological regulation; Synapsin I: A review of its distribution and biological regulation.

Descriptors :   *BRAIN, *PHOSPHOPROTEINS, *NEUROCHEMISTRY, ACTIVATION, ASSOCIATIVE PROCESSING, BIOCHEMISTRY, CALCIUM, CELLS(BIOLOGY), CENTRAL NERVOUS SYSTEM, CYCLIC COMPOUNDS, FIBROBLASTS, INTERNATIONAL, IONS, IRIS, LEARNING, LIPIDS, MEMBRANES(BIOLOGY), METABOLISM, MODULATION, MOLECULAR PROPERTIES, MUSCLES, NERVE CELLS, NERVES, NERVOUS SYSTEM, NUCLEOTIDES, PHOSPHORYLATION, PINEAL GLAND, PROTEINS, RABBITS, RATS, RESPONSE(BIOLOGY), SENSE ORGANS, SIGNALS, SYNAPSE, TISSUES(BIOLOGY), GROWTH(PHYSIOLOGY), NERVE TRANSMISSION.

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE