Accession Number : ADA186883

Title :   Management of Hard Tissue Avulsive Wounds and Management of Orofacial Fractures.

Descriptive Note : Annual rept. 1 Jun 83-31 May 84,

Corporate Author : BATTELLE COLUMBUS DIV OH

Personal Author(s) : Hassler, Craig R ; Markhoff, Carole J

PDF Url : ADA186883

Report Date : 31 May 1984

Pagination or Media Count : 17

Abstract : Research studies were conducted to produce and evaluate a high-quality directional porosity resorbable calcium phosphate ceramic material for use in the management of hard tissue avulsive wounds and orofacial fractures. The previous efforts demonstrated that directional porosity would allow adequate ingrowth of bone through the biomaterial prior to loss of mechanical integrity of the biomaterial. The overall objective is to produce a completely resorbable biomaterial which will promote bone formation and via a bone remodeling-- biodegradation process be completely replaced by bone. The biomaterial should allow bone ingrowth and provide mechanical integrity of the area under repair during the remodeling, biodegradation process. The dissolution of the biomaterial and bone formation need to proceed in a parallel and controlled fashion, so that mechanical integrity of the area under repair is not lost. In early studies, omnidirectional structural material would, depending upon chemical composition, either: not entirely biodegrade, or would degrade until mechanical integrity was lost. Unidirectional materials, as reported previously in our Annual Reports were free of these problems; ingrowth and subsequent bioresorption without loss of implant integrity was noted. Keywords: Osteogenesis; Surgery; Bioengineering.

Descriptors :   *WOUNDS AND INJURIES, *BONE FRACTURES, *CERAMIC MATERIALS, *SURGICAL IMPLANTATION, BIODETERIORATION, BIOENGINEERING, BONES, CHEMICAL COMPOSITION, CONSTRUCTION MATERIALS, DIRECTIONAL, FACE(ANATOMY), GROWTH(PHYSIOLOGY), HARDNESS, LOSSES, MANAGEMENT, MECHANICAL PROPERTIES, MOUTH, OMNIDIRECTIONAL, OSTEOGENESIS, POROSITY, REPAIR, SURGERY, TISSUES(BIOLOGY), UNIDIRECTIONAL, CALCIUM COMPOUNDS, PHOSPHATES

Subject Categories : Medicine and Medical Research
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE