Accession Number : ADA188700

Title :   Analysis of Trichothecene Mycotoxins by Combined HPLC/MS.

Descriptive Note : Annual summary rept. 15 Feb 85-15 Feb 86,

Corporate Author : NORTHEASTERN UNIV BOSTON MA

Personal Author(s) : Vouros, Paul ; Karger, B L

PDF Url : ADA188700

Report Date : 15 Apr 1986

Pagination or Media Count : 62

Abstract : The development of HPLC/MS assays for the analysis of selected trichothecene mycotoxins in urine is the goal of this program. T-2 toxin has been the initial target of this investigation. Three important issues have been addressed before proceeding with the actual HPLC/MS experiments: the synthesis of isotopically labelled internal standards, efficient recovery of the target compounds from the urine matrix, and determination of HPLC conditions for their separation. Keywords: Mass spectrometry, High performance liquid chromatography, Phytotoxins.

Descriptors :   *LIQUID CHROMATOGRAPHY, *MASS SPECTROMETRY, *PHYTOTOXINS, *URINE, EFFICIENCY, HIGH RESOLUTION, INTERNAL, RECOVERY, STANDARDS, SYNTHESIS, FUSARIUM

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE