Accession Number : ADA189941

Title :   Study of IL1 Structure Activity Relationship by Mass Spectrometry.

Descriptive Note : Annual rept. 1 Nov 86-31 Oct 87,

Corporate Author : HEALTH RESEARCH INC BUFFALO NY

Personal Author(s) : Cowens, J W

PDF Url : ADA189941

Report Date : 01 Nov 1987

Pagination or Media Count : 11

Abstract : The initial studies outlined in this report demonstrate that Biemann's approach to the sequencing of polypeptides by gas chromatography-mass spectrometry can be carried out on the bench top gas chromatograph-mass spectrometer - data system developed by Hewlett Packard. This technique has been used to determine the complete primary structure of glucagon and 50% of the primary structure of Tumor Necrosis Factor.

Descriptors :   *GAS CHROMATOGRAPHY, *MASS SPECTROMETRY, *PEPTIDES, *POLYMERS, GLUCAGON, INFORMATION SYSTEMS, NECROSIS, NEOPLASMS

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE