Accession Number : ADA192324

Title :   Examination of Iotophoretic Transport of Ionic Drugs across Skin.

Descriptive Note : Technical rept.,

Corporate Author : UTAH UNIV SALT LAKE CITY DEPT OF CHEMISTRY

Personal Author(s) : Pons, Stanley ; Higuchi, W I ; Masada, T ; Rohr, U ; Fox, J

PDF Url : ADA192324

Report Date : 30 Jul 1986

Pagination or Media Count : 16

Abstract : The purpose of this paper is to describe the systematic development of a new four-electrode system for studying iontophoresis of single charged drugs across the skin. It is also a critical examination of an equation which we have derived and which describes fundamentally flux enhancement across an artificial membrane or skin: Keywords: Transdermal drug delivery system.

Descriptors :   *DRUGS, *MEMBRANES, EQUATIONS, FLUX(RATE), OPTIMIZATION

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE