Accession Number : ADA192696
Title : Dermal Sensitization Potential of a Schistosome Topical Antipenetrant Lotion in Guinea Pigs.
Descriptive Note : Rept. for 15 Sep-2 Nov 87,
Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
Personal Author(s) : Frost, Denzil F ; Magnuson, Dean K ; Korte, Don W , Jr
PDF Url : ADA192696
Report Date : Mar 1988
Pagination or Media Count : 38
Abstract : A schistosome topical antipenetrant lotion, containing 1% niclosamide, was tested for its potential to produce dermal sensitization. The Guinea Pig Maximization Test was used to evaluate dermal sensitization potential. Grade II (mild) dermal sensitization to the lotion was obtained in this study. These results suggest that there is probable risk that the schistosome topical antipenetrant lotion will induce contact sensitivity in humans.
Descriptors : *SKIN(ANATOMY), *OINTMENTS, GUINEA PIGS, PROBABILITY, RISK, SCHISTOSOMA, SENSITIVITY, PENETRATION, PROTECTION, PREVENTIVE MEDICINE
Subject Categories : Pharmacology
Anatomy and Physiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE