Accession Number : ADA193087

Title :   The Role of Cytomegalovirus As a Cofactor in the Development of ARC-AIDS.

Descriptive Note : Annual rept. 29 Sep 86-28 Sep 87,

Corporate Author : TEXAS UNIV HEALTH SCIENCE CENTER AT SAN ANTONIO DEPT OF MICROBIOLOGY

Personal Author(s) : Smith, Kendall O ; Ratner, Joan M

PDF Url : ADA193087

Report Date : Oct 1987

Pagination or Media Count : 15

Abstract : This report displays the results of one year's longitudinal study of cytomegalovirus (CMV) as a candidate triggering cofactor in the development of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus differentiate triggering from opportunistic roles of CMV in HIV-infected people. Saliva and urine specimens are being cultured in MRC-5 human fetal lung cells, white blood cells are being stored in DMSO for later revival and study, and plasma or serum specimens are being studied for CMV-specific IgG and IgM. Western blot (W.B.) analysis is being done on each subject to determine the patterns of antibody response to over 25 CMV antigens.

Descriptors :   *CYTOMEGALOVIRUS, *VIRUS DISEASES, *IMMUNOLOGY, ANTIBODIES, ANTIGENS, BLOOD SERUM, LEUKOCYTES, PATTERNS, RESPONSE(BIOLOGY), SALIVA, URINE, ABNORMALITIES, IMMUNOGLOBULINS, PATHOGENESIS, CULTURES(BIOLOGY), AIR FORCE PERSONNEL

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE