Accession Number : ADA194459

Title :   Ionic Basis of Potential Regulation.

Descriptive Note : Final rept. 1 Jun 85-30 Sep 87,

Corporate Author : BAYLOR COLL OF MEDICINE HOUSTON TX DEPT OF PHYSIOLOGY AND MOLECULAR BIOPHYSIC S

Personal Author(s) : Chang, Donald C

PDF Url : ADA194459

Report Date : Jan 1988

Pagination or Media Count : 7

Abstract : The objectives of this contracted research is to understand the mechanisms by which the resting potential of the nerve cell is controlled. The following is a summary of the major findings of this contracted research: A new understanding of the physiochemical basis of potential regulation at the resting state. A new type of K channel that controls the resting potential of the nerve axon. Ion-selectivity of the delayed rectifier K channel in squid axon. Potassium efflux through the resting channel of squid axons. Evidence of a Mg-activated channel which appears only in intact squid axons but not internally perfused axons.

Descriptors :   *PHYSICOCHEMICAL PROPERTIES, *NERVE CELLS, NERVE FIBERS, NERVES, POTASSIUM, CHANNELS, POTENTIAL ENERGY, NEUROCHEMISTRY, CEPHALOPODA

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE