Accession Number : ADA194531

Title :   Study of the Effects of Drugs upon the Cardiovascular and Respiratory System.

Descriptive Note : Annual progress rept. 1 Jan-31 Dec 83,

Corporate Author : TENNESSEE UNIV CENTER FOR THE HEALTH SCIENCES MEMPHIS

Personal Author(s) : Caldwell, Robert W ; Nash, Clinton B

PDF Url : ADA194531

Report Date : 01 Feb 1984

Pagination or Media Count : 26

Abstract : During this past year we have: 1. Performed pilot experiments to define the cardiopulmonary actions of the candidate drug, WR-6026 and re-examined the cardiovascular and Pulmonary Effects of WR-6026. A copy of this protocol (originally submitted on 5 August, 1983) is attached. Performed the entire experimental protocol for both drugs (WR-6026 and Primaquine). We are currently in the process of tabulating and analyzing data from these experiments. A comprehensive written report will be forwarded to our contract monitor at Walter Reed Army Institute of Research as soon as possible. A summary of our findings for these studies is attached. Keywords: Antimalarials; Antileishmanials; Blood pressure; Electrocardiography.

Descriptors :   *ANTIMALARIALS, *CARDIOVASCULAR SYSTEM, *PRIMAQUINE, *RESPIRATORY SYSTEM, BLOOD PRESSURE, CONTRACTS, DRUGS, ELECTROCARDIOGRAPHY, HEART, LUNG, MONITORING, PILOTS, PHYSIOLOGICAL EFFECTS, HEART RATE

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE