Accession Number : ADA195589

Title :   Study of the Effects of Drugs upon the Cardiovascular and Respiratory Systems: Evaluation of Pulmonary and Cardiovascular Effects of Drugs of Military Interest.

Descriptive Note : Final rept. 1 Nov 82-15 Apr 86,

Corporate Author : TENNESSEE UNIV CENTER FOR THE HEALTH SCIENCES MEMPHIS

Personal Author(s) : Caldwell, Robert W ; Nash, Clinton B

PDF Url : ADA195589

Report Date : 01 Jun 1986

Pagination or Media Count : 13

Abstract : The Study of the cardiopulmonary actions of WR-6026 and Primaquine was completed and submitted 2 March 1984. The Study of the Determination of the Involvement of Histamine in the Blood Pressure Response to Liposome was completed and submitted 15 March 1985. The Study of the Cardiovascular and Pulmonary Effects of Pyridostigmine Bromide in the Dog: Correlation with Blood Cholinesterase Inhibition was completed and submitted February 1986. Keywords: Toxic tolerances; Antimalarials; Respiration; Blood pressure; Liposomes; Hypotension; Pyridostigmine bromide; Cholinesterase inhibitors; Drug toxicity; Pulmonary function; Pharmacology; Physiology. (kt)

Descriptors :   *CARDIOVASCULAR SYSTEM, *DRUGS, *RESPIRATORY SYSTEM, ANTIMALARIALS, BLOOD, BLOOD PRESSURE, BROMIDES, CARBAMATES, CHOLINESTERASE, CHOLINESTERASE INHIBITORS, CYTOPLASM, DETERMINATION, DOGS, HISTAMINE, HYDROXYL RADICALS, HYPOTENSION, INHIBITION, LUNG, METHYL RADICALS, PHARMACOLOGY, PHYSIOLOGY, PRIMAQUINE, PULMONARY FUNCTION, PYRIDINES, RESPIRATION, RESPONSE, TOXIC TOLERANCES, TOXICITY

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE