Accession Number : ADA195817

Title :   Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Descriptive Note : Annual rept. 1 Sep 84-31 Aug 85,

Corporate Author : INSTITUTE OF VIROLOGY OXFORD (ENGLAND)

Personal Author(s) : Bishop, David H

PDF Url : ADA195817

Report Date : 10 Feb 1988

Pagination or Media Count : 12

Abstract : Evidence has been obtained that Punta Toro (PT) virus, a member of the Phlebotomus fever serogroup of viruses (Phleboviruses, Bunyavidirae) has 3 virion RNA species (large, L, medium, M, and small, S), which are comparable in number to those of other members of the Bunyaviridae family, but different in size by comparison to the size of the S RNA of Bunyavirus genus members of the family. Studies supported by this grant report the coding strategies of the PT viral M and S RNA species and the characterization of their MRNA species. The amino terminal sequences of the G1 and G2 proteins have been mapped to the viral RNA sequence and the data compared to the M RNA sequence information of the Rift valley fever (RVF) virus obtained by USAMRIID staff and other contractees (Dr M. Collett). Keywords: Virus vaccines. (kt)

Descriptors :   AMINES, CODING, GENETICS, MOLECULES, RIBONUCLEIC ACIDS, RIFT VALLEY FEVER, SANDFLY FEVER VIRUS INFECTION, SEQUENCES, STRATEGY, VACCINES, VIRUSES

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE