Accession Number : ADA201835

Title :   Molecular Biology of STLV-III and HTLV-IV.

Descriptive Note : Annual rept. 1 Jul 87-30 Jun 88,

Corporate Author : DANA-FARBER CANCER INST BOSTON MA

Personal Author(s) : Sodroski, Joseph

Report Date : 09 AUG 1988

Pagination or Media Count : 7

Abstract : Infectious Simian Immunodeficiency Virus (mac) proviruses have been cloned and are being characterized for pathogenic potential in vivo. Mutations in the genes encoding regulatory functions will be made to define the role of novel lentivirus genes in in vitro and in vivo replication and pathogenesis. Keywords: Virology; Molecular biology; Biochemistry; Human immunodeficiency virus; HTLV-IV; STLV-III; SIMIAN AIDS, Deoxyribonucleic acids, Plasmics, Reverse transcriptase, Cytopathology. (aw)

Descriptors :   *CLONES, *MOLECULAR BIOLOGY, *PATHOGENESIS, *VIRUSES, *IMMUNOSUPPRESSION, BIOCHEMISTRY, CYTOPATHOLOGY, DEOXYRIBONUCLEIC ACIDS, GENES, IN VITRO ANALYSIS, IN VIVO ANALYSIS, MUTATIONS, VIROLOGY.

Subject Categories : Genetic Engineering and Molecular Biology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE