Accession Number : ADA227945

Title :   Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever).

Descriptive Note : Annual rept. 10 Feb 89-9 Feb 90,

Corporate Author : KOREA UNIV SEOUL COLL OF MEDICINE

Personal Author(s) : Lee, Ho W.

Report Date : 29 JUN 1990

Pagination or Media Count : 51

Abstract : World-wide, about 200,000 people are hospitalized with Hemorrhagic fever with renal syndrome (HFRS) (3 - 10% fatality) each year. The etiologic agents of HFRS are Hantaan, Seoul and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul virus, occurs in Asia, and mild form, caused by Puumala virus, occurs in Europe. The reservoirs of hantaviruses are rodents and other small mammals. Global surveys of the distribution of hantaviruses and surveillance of HFRS are important for prevention of this highly fatal disease. A simple and rapid serologic diagnostic test for HFRS in the areas where hantaviruses exist is urgently needed. It is also important to investigate antigenic differences of strains of Hantavirus isolated from rodents caught in non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive rodents there. Keywords: Hantavirus, Hantaan, Seoul, Puumala virus, Global survey, Hemorrhagic diseases, High density, Particle agglutination. (js)

Descriptors :   *DISEASES, *HEMORRHAGIC FEVERS, AGGLUTINATION, ASIA, DISEASE VECTORS, EASTERN EUROPE, ETIOLOGY, EUROPE, GLOBAL, HANTAAN VIRUS, HIGH DENSITY, KIDNEYS, KOREA, MAMMALS, PARTICLES, PARTS, RODENTS, SIGNS AND SYMPTOMS, SURVEYS, VIRUSES.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE