Accession Number : ADA289298

Title :   The Sympathetic Nervous System and the Physiologic Consequences of Spacefight: A Hypothesis.

Descriptive Note : Interim Journal rept.,

Corporate Author : ARMSTRONG LAB BROOKS AFB TX AEROSPACE MEDICINE DIRECTORATE

Personal Author(s) : Robertson, David ; Convertino, Victor A. ; Vernikos, Joan

Report Date : AUG 1994

Pagination or Media Count : 9

Abstract : Many of the physiological consequences of weightlessness and the cardiovascular abnormalities on return from space could be due, at least in part, to alterations in the regulation of the autonomic nervous system. This article reviews the rationale and the evidence for an autonomic mediation of diverse changes occurring with spaceflight, including the anemia and hypovolemia of weightlessness, an the tachycardia and orthostatic intolerance on return from space. The increasing evidence that autonomic mechanisms underlie many of the physiological consequences of weightlessness suggests that new pharmacological approaches based on these findings may attenuate these unwanted effects.

Descriptors :   *CARDIOVASCULAR SYSTEM, *ANEMIAS, *AUTONOMIC NERVOUS SYSTEM, LOW LEVEL, WEIGHTLESSNESS, SPACE FLIGHT, HEART RATE, ABNORMALITIES, PHARMACOLOGY, BLOOD VOLUME, SYMPATHETIC NERVOUS SYSTEM, TACHYCARDIA.

Subject Categories : Medicine and Medical Research
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE