Accession Number : ADA291361

Title :   Detection and Clinicopathologic Correlation of Human Immunodeficiency Virus (HIV-1) Nucleic Acids and Antigens in Reticuloendothelial and Central Nervous System Tissues, by Immunohistochemistry, in Situ Hybridization, and Polymerase Chain Reaction.

Descriptive Note : Annual rept. 1 Oct 93-30 Sep 94,

Corporate Author : ARMED FORCES INST OF PATHOLOGY WASHINGTON DC

Personal Author(s) : Burke, Allen P.

PDF Url : ADA291361

Report Date : 15 DEC 1994

Pagination or Media Count : 7

Abstract : The initial goals of this project are to collect autopsy tissues from HIV-positive asymptomatic drug addicts who die unexpectedly from drug overdoses. A wide sampling of autopsy tissue will be subjected to various techniques in identifying and localizing HIV-1. The viral burden, cellular sites of replication and progression of viral disease will be studied.

Descriptors :   *HUMAN IMMUNODEFICIENCY VIRUSES, *CHAIN REACTIONS, *NUCLEIC ACIDS, TISSUES(BIOLOGY), DETECTION, CELLS, POLYMERIZATION, SITES, CLINICAL MEDICINE, CHEMISTRY, CORRELATION, SAMPLING, PATHOLOGY, IMMUNOLOGY, DRUGS, ANTIGENS, AUTOPSY, DRUG USERS, HISTOLOGY, HYBRIDIZATION.

Subject Categories : Medicine and Medical Research
      Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE