Accession Number : ADA292323

Title :   A Discrete-Event Simulation Model of Myocardial Electrical Activity: Mathematical Electrophysiology.

Descriptive Note : Final rept.,

Corporate Author : ARMSTRONG LAB BROOKS AFB TX AEROSPACE MEDICINE DIRECTORATE

Personal Author(s) : Howe, R. B.

PDF Url : ADA292323

Report Date : DEC 1994

Pagination or Media Count : 26

Abstract : This work unit was opened to provide a channel for in-house work on mathematical modeling and computer simulation of the electrocardiogram (ECG) and its underlying electrophysiology. This work was intended to complement work being done in contracted efforts aimed at model-based enhancement of ECG diagnostic criteria for detection of coronary artery disease in USAF aircrew members. Both the contract and in-house efforts have been terminated due to funding constraints and organizational shifts in research focus. In this technical paper, we report on the development of a simulation model of the depolarization and repolarization processes in the ventricles which was to be used as a cardiac electrical source model in simulations of the ECG, as well as attempt to provide some commentary regarding the relation of these efforts to broader contexts.

Descriptors :   *MATHEMATICAL MODELS, *ELECTROCARDIOGRAPHY, *ELECTROPHYSIOLOGY, COMPUTERIZED SIMULATION, SIMULATION, ORGANIZATIONS, DETECTION, FLIGHT CREWS, REPORTS, ELECTRICAL PROPERTIES, SHIFTING, DIAGNOSIS(GENERAL), DEPOLARIZATION, HEART, MYOCARDIUM, CORONARY DISEASE, CORONARY ARTERIES, VENTRICLES.

Subject Categories : Anatomy and Physiology
      Operations Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE