Accession Number : ADA292488

Title :   Cellular and Molecular Level Responses after Radiofrequency Radiation Exposure, Alone or in Combination with X-Rays or Chemicals.

Descriptive Note : Final rept. 1 Apr 91-30 Sep 94,

Corporate Author : TEXAS UNIV HEALTH SCIENCE CENTER AT SAN ANTONIO DEPT OF RADIOLOGY

Personal Author(s) : Meltz, Martin L. ; Natarajan, Mohan ; Prasad, Adapa V.

PDF Url : ADA292488

Report Date : 21 FEB 1995

Pagination or Media Count : 101

Abstract : This project was initiated to explore the potential bioeffects of microwave radiation, alone or in combination with ionizing radiation and chemicals. Over the time period of the project, an automated thermal control system, to be used for maintaining the temperature in tissue culture medium during microwave exposures, was designed, constructed, and software was created. While this was underway during the project period, numerous positive control biological experiments were performed on two different cell types, the Epstein Barr Virus transformed 244B human lymphoblastoid cell, and the freshly isolated peripheral human lymphocyte. The 244B cells were used to address the question of whether a physical agent, ionizing radiation, at low doses where cells would predominantly remain viable, would induce the DNA binding protein NF-kB, and/or four immediate early genes (IEG) (protooncogenes).

Descriptors :   *MICROWAVES, *X RAYS, *RADIOFREQUENCY, COMPUTER PROGRAMS, RADIATION, AUTOMATION, EXPOSURE(GENERAL), BIOLOGY, MOLECULAR STATES, CHEMICALS, PHYSICAL PROPERTIES, REACTIVITIES, CHROMOSOMES, IN VITRO ANALYSIS, REDUCTION, OXYGEN, RESPONSE, SIGNALS, PHYSIOLOGICAL EFFECTS, DOSAGE, TEMPERATURE CONTROL, CELLS(BIOLOGY), DOSE RATE, DISTORTION, LOW RATE, IONIZING RADIATION, LYMPHOCYTES, INDUCTION SYSTEMS, HYDROXYL RADICALS, CULTURE MEDIA, MELATONIN.

Subject Categories : Radiobiology
      Radiofrequency Wave Propagation

Distribution Statement : APPROVED FOR PUBLIC RELEASE