Accession Number : ADA296655

Title :   Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. Volume 22 Number 2, 1994.

Descriptive Note : Final rept.,

Corporate Author : CALIFORNIA UNIV SAN DIEGO LA JOLLA

Personal Author(s) : Chang, T. M. ; Riess, J. G. ; Winslow, R. M.

PDF Url : ADA296655

Report Date : MAY 1994

Pagination or Media Count : 265

Abstract : Aims and Scope. This journal covers artificial cells, blood substitutes, and immobilization biotechnology. The emphasis of this journal is to allow for interdisciplinary interactions. Therefore, we welcome approaches based on biotechnology, chemical engineering, medicine, surgery, biomedical engineering, basic medical sciences, chemistry and others. The following areas are particularly welcomed. (1) Immobilized bioreactants including cells culture, microorganisms, enzymes, drugs, receptors, sorbents, immunosorbents and other biologically active molecules. (2) Artificial cells, microcapsules, liposomes, nanoparticles and other carriers. (3) Blood substitutes from fluorocarbon, modified hemoglobin, encapsulated hemoglobin, synthetic heme, recombinant hemoglobin, and others. Chemistry, methods, in-vitro studies, in-vivo evaluations and clinical results. (4) Microencapsulation and other methods of immobilization of cells (e.g. hybridoma, endocrine cells and liver cells, etc.) or microorganisms. Cells immobilized by different approaches. Methods, evaluation, and applications. Cell culture technologies related to immobilization. Hybrid artificial organs based on cell cultures. (5) Enzyme replacement, enzyme therapy, immunosorption, detoxification, hemoperfusion, metabolite conversions and drug delivery. (6) Design, evaluation and clinical application of hemoperfusion, artificial kidneys, plasmapheresis, and other artificial replacements. (7) Synthetic and biological biomaterials related to artificial cells and immobilization biotechnology. Blood compatible materials. Synthesis, biocompatibility, blood compatibility and evaluations. (8) Biotechnologically derived biologically active molecules related to artificial cells and immobilization biotechnology. (9) Drug delivery systems.

Descriptors :   *BIOTECHNOLOGY, *CELLS(BIOLOGY), *BLOOD SUBSTITUTES, TEST AND EVALUATION, CONVERSION, DELIVERY, SYNTHESIS, MOLECULES, CELLS, ENZYMES, LIPOSOMES, CLINICAL MEDICINE, IN VITRO ANALYSIS, CHEMISTRY, MEDICINE, ABSORBERS(MATERIALS), ENCAPSULATION, REPLACEMENT, THERAPY, RESTRAINT, HYBRID SYSTEMS, LIVER, DRUGS, IN VIVO ANALYSIS, HEMOGLOBIN, SURGERY, CULTURE, CULTURES(BIOLOGY), BLOOD, BIOMEDICINE, METABOLITES, FLUORINATED HYDROCARBONS, DETOXIFICATION, CHEMICAL ENGINEERING, ORGANS(ANATOMY), ADSORBENTS, KIDNEYS, MEDICAL ENGINEERING, HYBRIDOMAS, RH INCOMPATIBILITY.

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE