Accession Number : ADA297414

Title :   The Ventriculo-Arterial Coupling Ratio During Transient Gz Events.

Descriptive Note : Journal article,

Corporate Author : NORTH DAKOTA STATE UNIV FARGO

Personal Author(s) : Crisman, R. P. ; Convertino, V. A. ; Offerdahl, C. D. ; Ewert, D. L.

PDF Url : ADA297414

Report Date : JUL 1995

Pagination or Media Count : 7

Abstract : It has been shown by Westerhof et al. that the ratio TIT (where pi = Rp*SAC and Rp is total peripheral resistance, SAC is systemic arterial compliance, and T is heart period) is approximately a constant in all mammals under resting conditions such that diastolic pressure is sufficiently high to assure adequate coronary perfusion. The aim of this study is to determine if the ratio TIT is constant under the transient condition of a rapid onset rate +Gz acceleration. We hypothesize that the ratio is held constant by the cardiovascular control system. Four male baboons were subjected to 10 second rapid onset +Gz profiles and aortic pressure and flow were recorded. Rp and C were calculated using a 2-element windkessel model and T was determined by the inverse of heart rate. All parameters were calculated on a beat-to-beat basis. It was found that the ratio increased very little at +2 Gz and increased dramatically at +3 and +5 Gz, disproving our hypothesis. This increase was due to large increases in peripheral resistance and changes in heart rate over the course of a Gz run. The increases are presumed to represent baroreceptor reflex response to the drop in aortic pressure experienced during +Gz stress. The ratio TIT returned to its initial resting value shortly after the +Gz stressor was removed.

Descriptors :   *ACCELERATION, *CARDIOVASCULAR SYSTEM, *AORTA, TRANSIENTS, RATIOS, CONTROL SYSTEMS, MAMMALS, RESISTANCE, RESPONSE, PRESSURE, INVERSION, MALES, HYPOTHESES, HEART RATE, SENSE ORGANS, BLOOD PRESSURE, REFLEXES, PERFUSION, BABOONS.

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Mechanics

Distribution Statement : APPROVED FOR PUBLIC RELEASE