Accession Number : ADA299335
Title : Influence of Parenteral Progesterone Administration on the Prevalence and Severity of Mastodynia in Active Duty Servicewomen. A Multi-Institutional Case-Control Study.
Descriptive Note : Annual rept.,
Corporate Author : TRIPLER ARMY MEDICAL CENTER HI
Personal Author(s) : Euhus, David M.
PDF Url : ADA299335
Report Date : 01 SEP 1995
Pagination or Media Count : 11
Abstract : Breast pain (mastodynia) afflicts more than 3O% of women attending surgical breast clinics. The pain can be quite severe and may impair job performance and interpersonal relationships. The use of progesterones in the treatment of mastodynia remains controversial, but commonly practiced in some settings. The literature supporting this approach is inconclusive because the studies typically involve only small numbers of patients and are generally uncontrolled. In addition, questions of medication compliance are never addressed. This study employs a validated survey instrument and a cross sectional design to assess the prevalence and severity of mastodynia in a large cohort of women receiving long acting parenteral progesterones and in an even larger group of age-matched controls. At the time of this writing, 11 gynecology and family practice clinics have obtained human use approval and are actively enrolling patients. Thus far, 1,300 patients have been enrolled, and 533 have returned completed questionnaires. Control arm accrual is currently underway as well, and, at the time of this writing, questionnaires have been mailed to 3,449 randomly selected, age-matched controls. Detailed analysis of the data generated by this study will provide an accurate measure of the prevalence of mastodynia among active duty service women, assess attitudes about medical care for mastodynia and either support or refute a role for progesterones in the prevention and treatment of this common condition.
Descriptors : *ACTIVE DUTY, *MAMMARY GLANDS, *PARENTERAL INFUSIONS, *PROGESTERONE, VALIDATION, HUMANS, SURVEYS, CROSS SECTIONS, USER NEEDS, PAIN, PATIENTS, MEDICAL SERVICES, WOMEN, QUESTIONNAIRES, INTERPERSONAL RELATIONS.
Subject Categories : Anatomy and Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE